Digital Pathology

This imaging technique allows samples to be analyzed in offices and labs away from the microscope facility and by many people simultaneously. Samples are scanned at sub-micron resolutions and stored as calibrated digital image scans on the network. 

This means that the microscope is only occupied for as long as it takes to collect the scans of the samples. In contrast, when using live imaging for analysis, the microscope and BIOQUANT are occupied for as long as it takes to collect the data.

To collect data, a scientist uses a computer with the BIOQUANT OSTEO software to retrieve and analyze the scans. This workstation is often located in an office or lab away from the microscopy facility. With a scan, BIOQUANT lets you measure at any magnification: even creating "virtual objectives" like 0.25x so you can see even the largest sections in one field of view.

There are many ways to image scans at different costs and with different amounts of automation.

BIOQUANT SCAN

BIOQUANT SCAN is automation software for the scanning of tissue sections and well plates.

It works in conjunction with one of the following scanning solutions:

The scans it creates store calibration data internally. When the scan in loaded on a BIOQUANT OSTEO system, the analysis software automatically calibrates itself. This guarantees that data collected are always reported in proper calibrated units, regardless of the magnification used to create the scan or the magnification used to collect the data.

Other Slide Scanners

There are many general purpose slide scanners on the market. Chances are, if your lab is associated with a hospital, there's a either an Aperio ScanScope or Hamamatsu Nanozoomer in the pathology core. These produce beautiful scans of histology mounded on standard 1x3 glass slides. Both have freely available software for viewing the images and exporting scans to standard TIF formats.

Microsoft Image Composite Editor

 Montage creation in Microsoft Image Composite Editor

Montage creation in Microsoft Image Composite Editor

The Microsoft Image Composite Editor may be a solution for stitching images together exported from third party capture software, or exported from BIOQUANT, if you do not have BIOQUANT SCAN and one of the Microscope Upgrade Kits.

As part of it's Research Labs division, Microsoft has create the free Image Composite Editor, a software solution for creating a seamless beautiful large image out of many smaller overlapping images.

It exports BMP and JPG images which can be analyzed in BIOQUANT OSTEO.