Glenoid component loosening is a commonly encountered complication of total shoulder replacements. Therefore, focus has been placed on glenoid fixation. Porous metal implants, which promote biological fixation through osteointegration, have provided an uncemented alternative to the traditional cemented implant. In this explantation study, the authors examined the bone ingrowth and ongrowth of a specific porous titanium glenoid peg. Six explanted polyethylene glenoid components with porous titanium-coated central pegs were identified in the authors' implant retrieval program via retrospective review.
The effect of depositing a collagen (CG)-poly-ε-caprolactone (PCL) nanofiber mesh (NFM) at the microgrooves of titanium (Ti) on the mechanical stability and osseointegration of the implant with bone was investigated using a rabbit model. Three groups of Ti samples were produced: control Ti samples where there were no microgrooves or CG-PCL NFM, groove Ti samples where microgrooves were machined on the circumference of Ti, and groove-NFM Ti samples where CG-PCL NFM was deposited on the machined microgrooves.
Type I collagen and hyaluronic acid are both the main components of bone extracellular matrix, and play important roles in regulating a cell's behavior. In this study, the synergistic effects of type I collagen (Col) and hyaluronic acid (HA) on the biological properties of Col/HA-multilayer-modified titanium coatings were investigated.
Bacitracin immobilized on the titanium (Ti) surface significantly improves anti-bacterial activity and biocompatibility in vitro. In the current study, we investigated the biologic performance (bactericidal effect and bone-implant integration) of bacitracin-modified Ti in vivo.