cortical defect

Osteoblast-targeted disruption of glucocorticoid signalling does not delay intramembranous bone healing

Glucocorticoids at pharmacological doses have been shown to interfere with fracture repair. The role of endogenous glucocorticoids in fracture healing is not well understood. We examined whether endogenous glucocorticoids affect bone healing in an in vivomodel of cortical defect repair.